|
Symbol Name ID |
H2-Aa
histocompatibility 2, class II antigen A, alpha MGI:95895 |
| Darker colors indicate more annotations |
| Human Phenotypes | Increased circulating IgA level |
Increased circulating IgM level |
Abnormality of blood and blood-forming tissues |
Bleeding with minor or no trauma |
Epistaxis |
Gingival bleeding |
Gastrointestinal hemorrhage |
Hematemesis |
Melena |
Intracranial hemorrhage |
Intraventricular hemorrhage |
Joint hemorrhage |
Muscle hemorrhage |
Oral cavity bleeding |
Persistent bleeding after trauma |
Bruising susceptibility |
Purpura |
Petechiae |
Spontaneous hematomas |
Bone marrow hypocellularity |
Pancytopenia |
Aplastic anemia |
Abnormal erythrocyte enzyme concentration or activity |
Erythroid hyperplasia |
Reticulocytosis |
Anemia |
Hemolytic anemia |
Iron deficiency anemia |
Leukocytosis |
Leukopenia |
Abnormal granulocyte morphology |
Abnormal basophil morphology |
Acute lymphoblastic leukemia |
Ph-positive acute lymphoblastic leukemia |
T-cell acute lymphoblastic leukemias |
Chronic myelogenous leukemia |
Myeloproliferative disorder |
Arterial thrombosis |
Thromboembolism |
Venous thrombosis |
Deep venous thrombosis |
Mesenteric venous thrombosis |
Reduced factor VIII activity |
Prolonged partial thromboplastin time |
Thrombocytopenia |
Autoimmune thrombocytopenia |
Thrombocytosis |
Lymphoma |
Gastric lymphoma |
Elevated erythrocyte sedimentation rate |
Asplenia |
Splenic rupture |
Splenomegaly |
| Disease(s) Associated with HLA-DQA1 | |||||||||||||||||||||||||||||||||||||||||||||||||||||
| acute lymphoblastic leukemia | |||||||||||||||||||||||||||||||||||||||||||||||||||||
| antiphospholipid syndrome | |||||||||||||||||||||||||||||||||||||||||||||||||||||
| aplastic anemia | |||||||||||||||||||||||||||||||||||||||||||||||||||||
| autoimmune polyendocrine syndrome type 2 | |||||||||||||||||||||||||||||||||||||||||||||||||||||
| chronic myeloid leukemia | |||||||||||||||||||||||||||||||||||||||||||||||||||||
| congenital toxoplasmosis | |||||||||||||||||||||||||||||||||||||||||||||||||||||
| extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue | |||||||||||||||||||||||||||||||||||||||||||||||||||||
| factor VIII deficiency | |||||||||||||||||||||||||||||||||||||||||||||||||||||
| paroxysmal nocturnal hemoglobinuria | |||||||||||||||||||||||||||||||||||||||||||||||||||||
| primary biliary cholangitis | |||||||||||||||||||||||||||||||||||||||||||||||||||||
| rheumatoid arthritis |
| Mouse Phenotypes | enlarged thymus |
thymus hyperplasia |
decreased CD4-positive, alpha-beta T cell number |
increased CD8-positive, alpha-beta T cell number |
abnormal T cell morphology |
abnormal MHC II cell surface expression on macrophages |
abnormal splenocyte physiology |
|
| Availability | Mouse Genotype | |||||||
| H2-Aab-tm1Blt/H2-Aab-tm1Blt | ||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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